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Mana Battery: Cheaper, longer lasting batteries for clean energy

This company is set to spark a renewable energy revolution. Founded by Chunmei Ban, associate professor in the Paul M. Rady Department of Mechanical Engineering, along with CU alumni Nick Singstock and Tyler Evans, Mana Battery is developing a cheaper, safer and longer lasting alternative to the traditional lithium-ion battery.

Lithium-ion batteries are the most common type of rechargeable battery on the planet, powering everything from TV remotes to cell phones and even electric vehicles. But the materials used in these batteries, such as lithium and cobalt, are rare and expensive. In contrast, Mana’s batteries run on sodium, an abundant mineral, offering a more affordable and sustainable alternative.

Currently, sodium-ion batteries come with a host of technological challenges. For example, they typically store less energy than lithium-ion batteries of the same size. 

Ban and her team are working on improving sodium-ion battery designs to increase the amount of energy they can store. Their goal is to develop sodium-ion batteries with the same energy density as lithium-ion batteries at just 35% to 75% of the cost. 

The renewable energy industry could reap the benefits. Sodium-ion batteries could store excess clean energy generated by solar panels or wind turbines, providing power even during cloudy or windless days.  

“The use of batteries has significantly supported, and will continue to promote, the widespread use of electric vehicles and low-cost energy storage solutions for the power grid,” Ban said. 

Flari Tech: Laser-based nose to sniff out disease

Imagine a day when, instead of giving blood, saliva or other bodily fluids, you simply exhaled to get a read on what was happening with your health.

That’s the idea behind a new laser-based technology designed to harness human breath for faster, cheaper and less invasive medical diagnostics.

“There is a real, foreseeable future in which you could go to the doctor and have your breath measured along with your height and weight. … Or you could blow into a mouthpiece integrated into your phone and get information about your health in real time,” said Jun Ye, a JILA fellow and adjoint professor of physics who helped develop the technology along with physics doctoral candidate Qizhong Liang.

Humans exhale more than 1,000 distinct molecules with each breath, producing a unique chemical fingerprint or “breath print” filled with clues about what’s happening deep inside them. Scientists have long sought to harness that information, turning to dogs and other animals to sniff out cancer, diabetes and more.

Liang and Ye’s “frequency comb breathalyzer” could someday do the sniffing instead.

It uses frequency comb lasers, which feature narrow optical lines spread across a vast spectral window, to distinguish between different kinds of breath molecules, which are known to vary in concentration when people are sick. Paired with sophisticated algorithms for machine learning and data analysis, their laser-based nose has been shown to be able to detect whether someone has COVID-19 in a matter of seconds.

Research is underway, in close collaboration with medical doctors from the CU Anschutz Medical Campus, to see if breath can also be used to detect chronic obstructive pulmonary disease (COPD), pediatric respiratory issues and even lung cancer. The team also plans to miniaturize their technology.

In 2023, Flari Tech Inc.—named after the word ‘flari’ (“to smell”) in the Esperanto language—was formed to help move the technology from the lab to the bedside. Much more research is necessary, but ultimately the researchers believe their work could lead to earlier diagnoses for patients—and save lives.

Space Dust Research & Technologies: Tools for cleaning up dust on the moon

When future astronauts travel to the moon, they’ll face a little-known problem: The moon’s dust, or regolith, is made up of particles as sharp as glass that stick to everything.

“As we learned from the Apollo missions, lunar dust readily sticks to all surfaces of exploration systems, causing damage to spacesuits, degrading thermal radiators and solar panels and posing risks to crew health when inhaled,” said Xu Wang, a research associate at the Laboratory for Atmospheric and Space Physics (LASP) at CU Boulder.

Wang and Mihály Horányi, professor of physics and a researcher at LASP, launched a company to help. will pioneer technology known as Electron-beam Lunar Dust Mitigation (ELDM). ELDM devices generate a beam of electrons that add electric charges to those sticky particles of dust—causing them to, literally, jump off of surfaces.

This technology is versatile enough that it could work in handheld devices or in larger “car washes” that could clean entire spacesuits or rovers.

Space Dust Research & Technologies will also develop a separate type of technology that can sort through dust on the moon and arrange grains by size—an important step in mining regolith to turn it into building materials and more. The company’s work emerged out of years of research in LASP’s NASA-funded Institute for Modeling Plasma, Atmospheres and Cosmic Dust (IMPACT) lab.

Biosensor Solutions: Biodegradable sensors for tracking soil microbes

Scientists have long known that healthy soils and crops depend on vibrant communities of bacteria and other microbes living in the dirt. There’s just one problem: These microbial communities can be difficult to keep track of.

Until now. Engineer Gregory Whiting and his team at CU Boulder recently invented a way to measure soil microbial communities using low-cost, printed sensors. The trick: tasty electronics. The sensors include biodegradable resistors that soil microbes eat and degrade over time.

“It’s like a bait for microbes,” said Whiting, associate professor in the Paul M. Rady Department of Mechanical Engineering. “As they eat the device, the signal changes.”

That, in turn, could allow farmers to get a sense of how many microbes are in their soil.

The Boulder-based company , led by co-founders David Beitz and Carl Kalin, licensed this technology in 2024. The group is currently piloting the sensors with an initial group of local companies, precision agriculture providers and growers. According to company officials, “Data and insights from these new sensors will help growers increase yields and save resources on water, fertilizer, pesticides and herbicides.”

Mesa Quantum: Navigation devices based on the behavior of atoms

One new startup could make it easier to navigate the globe, even when GPS satellites go out, such as during bad storms.

For decades, scientists at the National Institute of Standards and Technology (NIST) have pioneered the technology of atomic clocks. These devices keep track of time and can help to track your location by measuring the behavior of electrons whizzing around atoms.

Svenja Knappe, associate research professor in the Paul M. Rady Department of Mechanical Engineering at CU Boulder, recently helped to improve on those inventions. She discovered a way to make atomic clocks more reliable while also shrinking them down to the size of a computer chip.

Sristy Agrawal and Wale Lawal, who founded Mesa Quantum in 2024, have high hopes for these chips. They say the company's atomic clocks could one day become part of a suite of technologies that enable GPS-free navigation—allowing anyone, from farmers to airplane pilots, to pinpoint their locations on Earth more reliably and precisely than ever before.

“The agricultural sector in Colorado relies heavily on GPS for the operation of tractors, irrigation systems and other modern equipment,” said Agrawal, who earned her doctorate in physics from CU Boulder in 2024. “As the industry moves toward greater automation, these systems will become even more dependent on precise and reliable positioning data.”