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Research Interests

• The neural mechanisms underlying emotional behavior and the stress-induced control of physiology and emotional behavior
• Behavioral Neuroendocrinology Laboratory

Education

• 1983-1987, B.A. Hons., University of Wyoming, Laramie, Wyoming
• 1987-1995, Ph.D., Oregon State University, Corvallis, Oregon

Professional Experience

• 1995-2002, Postdoctoral Research Fellow, University Research Centre for Neuroendocrinology, University of Bristol, Bristol, UK.
• 2002-2003, Neuroendocrinology Charitable Trust Research Fellow, University Research Centre for Neuroendocrinology, University of Bristol, Bristol, UK.
• 2003-2007, Wellcome Trust Intermediate Level Research Fellow, Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, University of Bristol, Bristol, UK.
• 2007-2013, Assistant Professor, Department of Integrative Physiology, University of Colorado, Boulder.
• 2013-Present, Associate Professor, Department of Integrative Physiology, University of Colorado, Boulder.

Honors and Awards

• 1983-1987, University of Wyoming Honors and Scholars Program
• 1992-1994, National Institute of Mental Health National Research Service Award (NRSA) Predoctoral Fellowship
• 2002-2003, Research Fellow, Neuroendocrinology Charitable Trust
• 2003-2007, Research Fellow, The Wellcome Trust
• 2007, Young Investigator Award, NARSAD
• 2009-2014, National Science Foundation (NSF) CAREER Award
• 2010, Young Investigator Award, NARSAD
• 2011, Anxiety Disorders Association of America (ADAA) Donald F. Klein Early Career Investigator Award
• 2016, University of Colorado Boulder Provost's Faculty Achievement Award (tenured faculty)

Recent Publications

For a complete list of publications,Ìý.

• Postolache TT, AkramÌýF, LeeÌýEE,ÌýLowryÌýCA, StillerÌýJW, Brenner LA, StreetenÌýEA, TureckiÌýG,ÌýDwivediÌýY. Increased brain vitamin D receptor expression and decreased expression of cathelicidin antimicrobial peptide in individuals who died by suicide.ÌýJÌýPsychiatrÌýRes.ÌýPMID: 32213352

• PostolacheÌýTT, WadhawanÌýA, CanÌýA,ÌýLowry CA, WoodburyÌýM, MakkarÌýH, HoisingtonÌýAJ, ScottÌýAJ, PotockiÌýE, BenrosÌýME,ÌýStillerÌýJW.ÌýInflammation in Traumatic Brain Injury.ÌýJÌýAlzheimers Dis. PMID: 32176646Ìý

• BernabeÌýCS, CalimanÌýIF, TruittÌýWA, MoloshÌýAI,ÌýLowryÌýCA, Hay-SchmidtÌýA, ShekharÌýA,ÌýJohnsonÌýPL. Using loss- and gain-of-function approaches to target amygdala-projecting serotonergic neurons in the dorsal raphe nucleus that enhance anxiety-related and conditioned fear behaviors.ÌýJ Psychopharmacol.ÌýPMID: 32153226

• Hagerty SL, Hutchison KE, Lowry CA, Bryan AD. An empirically derived method for measuring human gut microbiome alpha diversity: Demonstrated utility in predicting health-related outcomes among a human clinical sample.ÌýPLoS One.ÌýPMID: 32119675

• BowersÌýSJ, VargasÌýF, GonzálezÌýA, HeÌýS, JiangÌýP, DorresteinÌýPC, KnightÌýR, Wright KPÌýJr,ÌýLowryÌýCA, FleshnerÌýM, VitaternaÌýMH,ÌýTurekÌýFW. Repeated sleep disruption in mice leads to persistent shifts in the fecal microbiome and metabolome.ÌýPloS One.ÌýPMID: 32078624

• AkramÌýF, GragnoliÌýC, Raheja UK, SnitkerÌýS,ÌýLowry CA, Stearns-YoderÌýKA, HoisingtonÌýAJ, BrennerÌýLA, SaundersÌýE, StillerÌýJW, RyanÌýKA, RohanÌýKJ, MitchellÌýBD,ÌýPostolacheÌýTT. Seasonal affective disorder and seasonal changes in weight and sleep duration are inversely associated with plasma adiponectin levels.ÌýJÌýPsychiatr Res.ÌýPMID: 31981963

• Wadhawan A, Reynolds MA, Makkar H, Scott AJ, Potocki E, Hoisington AJ, Brenner LA, Dagdag A,ÌýLowry CA, Dwivedi Y, Postolache TT. Periodontal pathogens and neuropsychiatric health.ÌýCurr Top Med Chem.ÌýPMID: 31981963

• Amoroso M, Böttcher A,ÌýLowry CA, Langgartner D, Reber SO. SubcutaneousÌýMycobacterium vaccaeÌýpromotes resilience in a mouse model of chronic psychosocial stress when administered prior to or during psychosocial stress.ÌýBrain Behav Immun.ÌýPMID: 31887415

• Prescott SL, Hancock T, Bland J, van den BOsch M, Jansson JK, Johnson CC, Kondo M, Katz D, Kort R, Kozyrskyj A, Logan AC,ÌýLowry CA, Nanan R, Poland B, Robinson J, Schroeck N, Sinkkonen A, Springmann M, Wright RO, Wegienka G.ÌýInt J Environ Res Public Health.ÌýPMID: 31694316

• Akram F, Jennings TB, Stiller JW,ÌýLowry CA, Postolache TT. Mood Worsening on Days with High Pollen Counts is associated with a Summer Pattern of Seasonality.ÌýPteridines.ÌýPMID: 31631951

• Duffy AR, O'Connell JR, Pavlovich M, Ryan KA,ÌýLowry CA, Daue M, Raheja UK, Brenner LA, Markon AO, Punzalan CM, Dagdag A, Hill DE, Pollin TI, Seyfang A, Groer MW, Mitchell BD, Postolache TT.ÌýToxoplasma gondiiÌýSerointensity and Seropositivity: Heritability and Household-Related Associations in the Old Order Amish.ÌýInt J Environ Res Public Health.ÌýPMID: 31623376

• Arnold MR, Greenwood BN, McArthur JA, Clark PJ, Fleshner M,ÌýLowry CA.ÌýEffects of repeated voluntary or forced exercise on brainstem serotonergic systems in rats.ÌýBehav Brain Res.ÌýPMID: 31525404

• Flux MC,ÌýLowry CA.ÌýFinding intestinal fortitude: Integrating the microbiome into a holistic view of depression mechanisms, treatment, and resilience.ÌýNeurobiol Dis.ÌýPMID: 31454550

• Donner NC, Davies SM, Fitz SD, Kienzle DM, Shekhar A,ÌýLowry CA. Crh receptor priming in the bed nucleus of the stria terminalis (BNST) induces tph2 gene expression in the dorsomedial dorsal raphe nucleus and chronic anxiety.ÌýProg Neuropsychopharmacol Biol Psychiatry.ÌýPMID: 31415826

• Lieb MW, Weidner M, Arnold MR, Loupy KM, Nguyen KT, Hassell JE Jr, Schnabel KS, Kern R, Day HEW, Lesch KP, Waider J,ÌýLowry CA. Effects of maternal separation on serotonergic systems in the dorsal and median raphe nuclei of adult male Tph2-deficient mice.ÌýBehav Brain Res.ÌýPMID: 31319134